When pharmaceutical companies wish to market a drug, there is a legislative requirement that they first demonstrate efficacy and safety. The pharmaceutical companies do this by contracting out clinical trials. The history of these trials is one of refinement over time with the most recent trials meeting rigorous requirements for blinding (i.e. neither the participants nor the experimenters know who’s getting what kind of treatment) and randomisation (i.e. random allocation of participants to the different treatments).
I was listening to an old Skeptics Guide to the Universe (SGU) podcast from October 13th 2010 which featured an interview with Ben Goldacre, a psychiatrist, medical writer and author of the excellent blog/column/book Bad Science. He made an argument that resonated so strongly that I have to reproduce it in its entirety:
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